Category Archives: Mental Health

The Amazing Power of Music Therapy


When I was a child, on most Fridays, my dad, mom, brother and I would travel to Cape Cod to visit my grandparents. For my father, this drive would come after a long day of work, during which he had already commuted from our home, an hour outside of the city, to Boston, where he worked as an accountant, and back home again. He was an intense man, and during these drives to the Cape we were often silent, on edge – unsure how to interpret his sullen and grave demeanor.

After we arrived, my grandmother would typically begin playing a mix of classical music, folk songs and pop songs on her spinet piano – and I would watch my dad’s face transform: his jaw would slacken, while the lines between his eyebrows softened, lifting the intensity of thought that always seemed to burden him.

This was my first experience of the power of music.

Nearly two decades later, I learned of music therapy as a profession. I was a rising junior in college and, without hesitation, I switched my major to learn how to clinically wield music’s ability to transform and heal – a power I had observed years earlier.

Music therapy has grown from relative obscurity to a practice that is becoming fairly mainstream, largely due to the advocacy of colleagues in the field, along with media coverage of the burgeoning profession. Jodi Picoult came to Berklee College to study music therapy to develop the main character – a music therapist – of her novel Sing You Home. Meanwhile, following the gunshot injury she sustained, Representative Gabby Giffords underwent rehabilitation efforts that included music-based interventions. Although she initially couldn’t speak, she could sing, an ability that was used to further her speech recovery. And films about music’s capacity for healing and improving quality of life include the recent releases Alive Inside, The Lady in Apartment 6, Landfill Harmonic and The Music Never Stopped.

The trailer for The Lady in Apartment 6. ‘My world is music,’ said the film’s subject, 109-year-old Alice Sommer. ‘I am not interested in anything else.’

Doctor-writer Oliver Sacks’ essay collections, like Musicophilia, introduced stories to the public that explained the ability of music to promote skill learning and/or recovery in the face of severe disability and trauma. Research in neuroscience has backed up many of Sacks’ observations. For example, people who have suffered strokes or have been diagnosed Parkinson’s disease are better able to walk while listening to rhythmic music. In the case of strokes, people who can’t talk can often sing. Singing is then used to facilitate recovery of speech. This has been the case of Representative Gabby Giffords.

Oliver Sacks’ essays – like those in the collection Musicophilia – have helped promote the benefits of music therapy.
Wikimedia Commons, CC BY-SA

Another study showed that premature babies in the neonatal intensive care unit left the ICU, on average, 11 days earlier if they used a device that played lullabies triggered by their sucking. And children who have had orthopedic surgery will report lower levels of pain when doctors offer post-operative music therapy.

In my practice as a speech language pathologist and music therapist, I’m able to use music to serve a variety of patients with an array of needs. Children with autism tend to be more attentive to musical sounds than speech sounds (especially when they’re very young), so I’ll use music to foster their linguistic and cognitive development. In my work with hospice patients, I’ll use quiet music that has a lulling rhythm to help even out their ragged breathing (which is sometimes very difficult for families to watch).

For cancer patients, I’ll use songs of hope and resilience. And by pairing music with imagery, such as relaxing nature images, I’ve helped patients preparing for surgery achieve a state of tranquility that can decrease their need for anesthesia and pain medication. I’ve used the same protocol to decrease the use of anti-anxiety medications among hospice patients I’ve served. Ultimately, carryover is the endgame: we help patients take the tools they’ve learned in music therapy and apply them to their everyday lives.

As a professor of music therapy at the Berklee College of Music, I’m preparing the next generation of music therapists to work in a variety of settings: early intervention programs, public schools, hospice and palliative care, cancer clinics, nursing homes and private practice. For many students, it’s an attractive opportunity – a chance to use their artistry to make the world a better place.

Every week, our Berklee students Skype with a group of child soldiers in Uganda. These young adults have suffered a great deal: forced to kill as children, they often started with their own family members and neighbors. They’ve emerged from the bush traumatized and without purpose. We’re teaching them to use meditative practices in music to calm their minds and to infuse meaning into their lives. As our students share therapeutic practices with the child soldiers, they, in turn, perform and share their music and dance for our students.

It’s this fusion of what many consider two distinct, incompatible entities – art and science – that ultimately elevates both; and the two, as one, can more readily accomplish their shared purpose: the healing and betterment of humanity.

The Conversation

This article was originally published on The Conversation.
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Toxic Bosses And Joyless Workplaces


The new boss proved an able negotiator, winning himself an outsize compensation and benefits package. They even bought him a mansion. But at his first and only party for employees, he roped off most of the interior and installed backyard porta-potties. He located his office in a separate building. And before long, his penchant for arriving at meetings late, leaving early and staying just long enough to pronounce his edicts became all too apparent. During his tenure, organizational morale and performance plummeted. In just 28 months, he was gone.

Just as effective bosses can do considerable good for an organization, toxic ones can inflict a great deal of damage. By toxic, I don’t just mean incompetent – I mean malignant.

Over the past few years, I have visited a number of universities, academic health centers and medical departments, collecting stories about toxic bosses along the way. Many of these places are still struggling to claw their way out of the holes a toxic leader dug for them. The story that opens this article is just one of many I have encountered on my travels.

The first step to coping effectively with a toxic boss is recognizing that you have one. Here are 10 indicators that a new boss is probably toxic.

Meet the new boss.
Dementor via Alex Malikov/Shutterstock

  1. When a toxic boss comes on board, it feels as though all fellowship and joy are being sucked out of the organization. Like Dementors in Harry Potter, toxic bosses drain people of their passion, leaving nothing in their wake but a widespread sense of despair. Employees come to resemble mice who have been subjected to random electrical shocks, lapsing into a state that psychologists call learned helplessness. As another former employee of a toxic boss put it, “It wasn’t long before the whole organization took on a soulless feel.”

  2. Within weeks of the toxic boss’s arrival, the mercury in the organization’s “distrustometer” begins rising precipitously. People begin eying one another with suspicion. Lively meetings become deadened, as though no one would dare voice a divergent opinion. According to one employee, “People stopped saying what they really thought. If they ever spoke their mind, they did so only after glancing over both shoulders to make sure no one was listening, and then they spoke in a whisper. It was like Invasion of the Body Snatchers.“

    They look happy.
    Meeting via Peter Bernik/Shutterstock

  3. Power becomes consolidated in the hands of a few people who report directly to the toxic boss. People who question this process are moved aside or completely out of the organization. In many cases, the toxic boss achieves these ends not by direct confrontation, but like a subtle poisoner, delivering the lethal dose in tiny amounts that build up over time.

  4. Toxic bosses quickly seize control of the pathways along which knowledge is shared. Organization charts and reporting hierarchies are rearranged so that everything flows through one central hub, with few if any alternatives. Without admitting to it, toxic bosses feel threatened by more open patterns of information flow. As the former colleague of a toxic boss put it, “He sensed that if others knew what was really going on, his position, power and prestige would be undermined.”

  5. With a toxic boss, employees may have a hard time remembering why they came to work for the organization in the first place. The true mission of the organization is obscured. The toxic boss shifts everyone’s attention to crasser metrics, such as revenue and rankings, and the organization’s mission is treated as a mere tool for boosting results.

    The toxic boss in action.
    Image via Piotr Marcinski/Shutterstock

  6. Toxic bosses leave others feeling manipulated and used. Some are simply so insensitive that they do not appreciate the toll that their modus operandi takes on their colleagues, but others seem positively to revel in it. Said an employee, “She seemed to believe that the only way to make herself seem bigger was to make the people around her feel progressively smaller.”

    Another victim of the toxic boss.
    Images via goldyg/Shutterstock

  7. Soon after the toxic boss arrives, people begin disappearing. Almost invariably, such departures go unannounced, completely devoid of fanfare or explanation. One day they are there, and the next day they are gone, and only later do people learn that former colleagues were abruptly told one day to pack up their offices and hit the pavement. The toxic boss will never express gratitude to their service, publicly or personally.

  8. The toxic boss has no interest in what others have to say. Some savvy operators appear to listen to other perspectives, but when it comes to action, their in-boxes are black holes. They seem to believe that being an effective leader means being the center of attention. Before long, their behavior at meetings begins to reveal their true stripes. Said one former employee of a toxic boss, “She kept cutting other people off, belittling their contributions, and ended up listening to nothing but her own voice.”

  9. The toxic boss starts to act like a playground bully. People are treated not as sources of insight but as tools of implementation. When they diverge from this path, the toxic boss reminds them how easily they could be replaced. In short, the tools of persuasion give way to the instruments of coercion. And such techniques are powerfully augmented by the enhanced sense of vulnerability that accompanies the swelling ranks of the disappeared.

    The Pantopticon.
    Jeremy Bentham via Wikimedia Commons

  10. Do you feel like your every move is being watched by unseen eyes? Like you are in some kind of jail? Do you feel like your boss taking leadership lessons from Jeremy Bentham? His creation, the Panopticon is a building with a watchman sitting at the center, looking out on all the inmates, who are arrayed around the periphery, each in a separate cell. The inmates cannot see the jailer, generating a sense of constant surveillance.

Diagnosis: toxic boss. So what can you do?

One employee advised, “It is best to react with honesty and courage. Just point out the toxic boss’s impact and advocate as well as you possibly can for a decisive change of course.” One temptation to scrupulously avoid is fighting poison with poison. Don’t use toxic tactics to combat toxicity. This not only smacks of hypocrisy, it also compounds the problem by corroding the organization’s culture even further.

When this happens, toxic bosses win.

The Conversation

This article was originally published on The Conversation.
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Crowdfunding Brain Images of 20+ People Tripping Their Faces Off


Psychoactive recreational drugs are more popular than ever. They are just as dangerous as ever and while the tide is turning for marijuana, most recreational drugs are still illegal. In several academic circles psychoactive drugs are thought to hold a vast theraputic potential. In the near future we might see doctors prescribe psychadelics to treat a wide variety of mental health problems. Neuroscientists are starting to understand exactly what is happening to the brain when humans are under the influence and the rapidly developing field of understanding of consciousness isn’t afraid to embrace illegal drugs.

Cannabis nearly eradicates the symptoms of  attention deficit hyperactivity disorder, improve appetite and can safely, easily treat insomnia. The active compound of magic mushrooms, psilocybin, might be able to treat addiction, obsessive-compulsive disorders, narcissism and possibly depression; MDMA instigates vast improvement in PTSD, and is now being tested to treat Parkinson’s; LSD alleviates anxiety, helps people work toward sobriety when they struggle with alcoholism and can be used to treat inflammatory disorders. Ketamine, aka  ‘Special K’ has been used as an anesthetic in both animals and humans, but newer data has indicated it may be an effective treatment for mood disorders. It’s developed a reputation for snapping people out of a suicidal thought pattern or the downward turn of bipolar disorder in as little as a couple hours.

It is notoriously difficult to obtain legal permissions and research grants in order to further study these substances. In fact, the biggest obstacle to their study is public opinion, which ultimately changes the way grant money flows and influences the minds of lawmakers.

In these turbulent times, science is gaining new purchase in the public mind, and that could mean new studies funded and performed above-board with such controversial but ultimately easily controlled substances such as  LSD, Ketamine and psilocybin. In order to understand their effectiveness as medicine or research drugs, modern neuroscientists and behavioural psychologists are studying not just the behavior of human test subjects but the phsyiological changes in their brains.

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David Nutt teaches neuropsychopharmacology at  Imperial College London is also a former government chief drug adviser. The turbulent landscape of grant money in the UK has lead his quest for proper funding to the modern, online crowd-funding market. Nutt is currently using a start-up science crowdfunding platform called Walacea to gather financial support for his LSD research, a project which is underway in collaboration with Imperial College London and the Beckley Foundation.

“Despite the incredible potential of this drug to further our understanding of the brain, political stigma has silenced research we must not play politics with promising science that has so much potential for good.” ~ David Nutt

To date, 20 subjects have been dosed with LSD and undergone complex  imaging studies via combination fMRI and MEG image hardware. These techniques both measure brain function. fMRI records still images of of brain activity; MEG records moving images like a video.

LSD is expected to have similar effects to psilocybin, because both are thought to reducs blood flow to certain parts of the brain to dampening their activity, removing control measures that inhibit neural connectivity. Psilocybin appears to encourage brain areas  normally distinctly unrelated to communicate with one another, which is thought to create the famous effect psychedelics have on creativity. If the crowd-funding operation goes as intended, there should be money enough to get a larger sample size and find out if LSD can live up to the hope. Check out Nutt’s pitch in the video below~!

 

Jonathan Howard
Jonathan is a freelance writer living in Brooklyn, NY

The House of Cards characters have terrible sleep habits


This article contains spoilers from season three of House of Cards.

It’s entirely possible that I’ve been staying up too late this week. After leaving the lab at the end of the day, I’ll head home to binge on the political drama House of Cards, the third season of which has been dumped onto our Netflix queues.

Simultaneously, the National Sleep Foundation is sponsoring Sleep Awareness Week from March 2nd to 8th, which makes me feel guilty for how poor my sleep hygiene has been lately. But perhaps I shouldn’t be too hard on myself – after all, I’m not the leader of the free world who needs to make rational, clear-headed decisions about my country on a daily basis.

Since the first episode of the show, I’ve been pretty appalled by the Underwoods’ poor sleep habits. So here are three simple sleep hygiene rules that Frank and his wife Claire would be wise to follow.

Get those laptops out of the bedroom

Rarely does an episode go by that we don’t see Claire lounging in bed, papers strewn across the blanket and MacBook screen glowing in the reflection of her wayfarers. Frank is guilty in a different way, suited up and typing away at his computer in the Oval Office in the middle of the night or playing games on his tablet. Reading and working late are one thing, but the blue light from their screens are probably destroying their bodies’ natural circadian rhythms.

The pineal gland is a small, pine cone-shaped structure near the center of the brain that secretes the hormone melatonin at night in response to darkness. While it is sensitive to all wavelengths of light, blue light in particular (460-480 nanometers) suppresses melatonin release proportional to both the intensity and duration of the light exposure. A 2006 study by Steven Lockley and colleagues at Harvard found that when participants were exposed to 6.5 hours of either blue or green light, blue light suppressed melatonin twice as long, shifting the circadian rhythm by three hours (versus 1.5 hours with green light). Blue light exposure also reduced delta, or “deep,” sleep at night.

Pineal gland, center.

Regardless of intensity, blue light – like that emitted from television, computer, tablet, e-reader, and phone screens – is wrecking our natural sleep and circadian rhythms. It’s estimated that 95% of Americans use some sort of electronic device at least one hour before bedtime. A study by Anne-Marie Chang and colleagues published in December found that compared to reading a paper book before bed, reading from an iPad increases sleep latency, decreases REM sleep, and enhances feelings of sleepiness during the day, even when both groups sleep the same duration the night before.

Shut off the screens at night, Mr President and First Lady. If you must work so late, consider downloading the application f.lux or investing in a pair of orange glasses to block out the blue.

Exercise is no replacement for sleep

Rarely do we see Claire run in daylight. In earlier seasons, she bustles around the kitchen in the wee hours of the morning in running spandex, and is later seen darting headstones in the dark graveyard.

In the middle of season three, we watch Claire go for a midnight run to ward off stress, flanked by security. And with his late-night indoor rowing habit, Frank isn’t off the hook either. The Underwoods are busy public figures, and incorporating vigorous exercise into their hectic schedules is to be commended – but not at the expense of their sleep.

Night rowing is a no-no.

Exercise is great for sleep. Indeed, a 2011 study reported that 150 minutes of moderate to vigorous physical activity per week improve can improve sleep quality by 65%. Using actigraphy, study authors Paul Loprinzi and Brad Cardinal examined the exercise habits of over 3,000 adult men and women. Those who met minimum physical activity requirements reported less daytime sleepiness and better overall sleep quality, regardless of factors like age, body weight, and depression. Similar findings on the benefits of exercise on sleep were reported by the National Sleep Foundation’s 2013 Sleep in America poll.

The timing of exercise is a little more controversial. It’s a common sentiment that late-night exercise destroys sleep. After all, exercise ramps up your heart rate, raises body temperature, and causes release of the stress hormone adrenaline, making us active and alert. A 2011 study, however, reported that participants slept just as well on nights when they exercised just half an hour before bed as they did on nights when they didn’t exercise at all. For those prone to bouts of insomnia, though, most sleep physicians recommend not exercising for several hours before bed.

Kudos on your exercise habits, Frank and Claire. You’re way more disciplined than I am. Just work on the timing a bit, okay?

Ditch the alcohol before bed

One of the silliest moments in season three is when Russian president Victor Petrov, on a visit to the US, challenges the White House dinner party to shot after shot of pricey vodka. Not long after, Claire and Secretary of State Cathy Durant play a friendly game of beer pong. What is this – the White House, or a college fraternity party?

No beer pong before bed.
Netflix

Alcohol has a strange, dichotomous effect on sleep. On the one hand, it helps us fall asleep faster and increases slow-wave, or deep, sleep during the first half of the night. The second half of the night is not so pretty, however.

In 1972, Williams and Salamy experimented with different concentrations of alcohol in the evening. Thirty to 60 minutes before bed – in an effort to yield peak blood alcohol concentrations at lights-out – participants were assigned to consume anywhere between one and six drinks. (A “drink” is defined as 350ml beer, 150ml wine, or 44ml of 80-proof distilled spirits.) Although those who consumed the most drinks fell asleep the fastest, they also woke up more frequently during the night.

Alcohol mimics gamma-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the brain. When bound to a GABA receptor on a neuron, alcohol allows either the influx of negative or efflux of positive ions, giving the cell a more negative charge. Thus, the neuron’s attempt to fire an action potential is thwarted. After an evening of drinking, GABA dominates the first half of the night, which explains why we fall asleep so deeply.

The bad news comes when GABA is recycled into glutamate, the brain’s major excitatory neurotransmitter. Once GABA is metabolized halfway through the night, glutamate-releasing brain regions like the reticular activating system – which, among other things, regulates sleep, waking and arousal – are likely to be where the midnight disruptions kick in.

Frank and Claire are a fascinating character study in power, ruthlessness, and the human condition. If you want to learn how to get to the top fast, take notes (minus the criminal bits, perhaps).

But if you want to improve your sleep hygiene, don’t take a page from their book. After all, if the Underwoods have trouble sleeping after their heads hit the pillow, it’s probably not their consciences keeping them awake.

The Conversation

This article was originally published on The Conversation.
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How Unemployment Can Change Your Life Permanently


Hearing the much dreaded words “you’re fired,” brings a whole whirlwind of questions, fears, and uncertainty – either to come before or after the outrage you might feel upon being told to clean out your desk. How many unemployment benefits do you qualify for? What will you do for bills? When are you going to start sending out the resume again and how do you make sure it sticks? How soon until job hunting itself seems to turn into a full-time, thankless job? Sure, the first few days you can spend sleeping in and watching TV as you plan your comeback, but now science has brought up yet another concern. Losing your job changes your life, that’s for sure, but a closer look suggests that it might change your mind and your brain too if you find yourself unemployed long enough.

A new study conducted by researchers at the American Psychological Association (APA) recently concluded that the effects of extended unemployment reach beyond the individual and their family in question – with consequences that are psychological and impact the individual in a number of socioeconomic ways for the long term. According to the research, long periods of unemployment may cause the individual to be less open-minded, less conscientious, and less agreeable, all traits that can potentially make it more difficult for them to find work again.

The researchers’ findings are a startling revelation for psychologists who long believed that people have fixed personalities that more or less remain the same throughout their lives, while giving weight to the theory that external forces can also greatly impact our own basic personality. In order to conduct the study, Christopher J. Boyce, who serves as a research fellow at the University of Stirling of the United Kingdom, along with his associates did an analysis of data taken from a survey done by the German Socio-Economic Panel Study, which have been cited in a number of clinical research efforts. They focused in on the responses of 6,769 participants, all residents of Germany, who had each undergone a personality assessment twice in four years, between 2006 to the end of 2009. During that period, approximately 3.1 percent of the total participants included in the study had been unemployed throughout the study’s entire four-year duration. An additional 3.7 percent of the applicants had been jobless periodically, each episode lasting for never more than several months, as they were quickly able to secure employment afterwards.

The research team looked at the survey answers, bearing in mind that the survey had been designed with the basic five personality traits used by psychiatrists to evaluate their patients — agreeableness, conscientiousness, extraversion, neuroticism, and openness. They then used the surveys to determine whether or not any personality changes evident over time on the survey were in any way related to unemployment – something that typically awards a significant amount of points on the Holmes and Rahe stress scale. With each survey, the researchers took into consideration how long the individual was jobless, already studied differences in gender, and also the levels of reemployment, before they came to their conclusions. Gender certainly proved to be a factor as well. In instances of chronic unemployment, men retained higher levels of agreeableness throughout the first two years of their unemployment, compared against employed men. However, these levels then declined after the first two years. The level of agreeableness declined among women, however, for each year they were jobless.

The longer the period of unemployment also had a positive correlation with low levels of conscientiousness for men. By comparison, jobless women were much more conscientious at the initial and latter stages of their unemployment, but did show signs of a lapse during the middle part. The researchers attributed this characteristic to be the result of women pursuing other activities to occupy their time with, an attempt to still feel productive throughout their unemployment. A similar relationship was shown with openness. Levels remained the same for men during the first year and then steadily declined for however long they remained jobless. Openness levels for unemployed women dropped throughout the second and third years, but after that, they went back to normal levels, which were reported in the 2009 assessments.

Boyce published his study in the Journal of Applied Psychology. He said that his team’s findings are a demonstration of why people as a society so often stigmatize unemployed individuals, due to these unfavorable changes. The result is often a rather vicious cycle. Even when these chronically unemployed people re-enter the work force, they may have a considerably more difficult time keeping a job, compared to those who were only unemployed for short amounts of time or have always managed to hold a steady job – one which can sometimes boil down to class differences. Studies have already showed the psychological effects that are often presented by poverty, and Boyce has called for state policy makers to take the new data into consideration.

James Sullivan
James Sullivan is the assistant editor of Brain World Magazine and a contributor to Truth Is Cool and OMNI Reboot. He can usually be found on TVTropes or RationalWiki when not exploiting life and science stories for another blog article.

Building a Better Anxiety Drug Through a Deeper Understanding of Protein Structure


MSU’s Center for Mitochondrial Science and Medicine funded modest research into TSPO, which recently turned out to be an important brain protein. The National Institutes of Health has now taken on much of the funding. So what’s this hot new discovery? A protein that has lead the psychiatric, medical and neuroscience communities to a new understanding of some of the most common brain disorders. Fei Li, MSU postdoctoral researcher and co-author of the university study, explains why a deeper understanding of this one protein is such a big breakthrough:

“One reason that TSPO’s function has been so hard to pin down is that many studies have been done in the complex and diverse environments of whole cells and tissues, where a clear-cut interpretation of the results is difficult,” said Fei Li,  “We were able to obtain a pure protein that was still functional, but isolated from these complications.”

The team of researchers extracted TSPO proteins from bacteria instead of humans, but the protein is nearly identical. The scientists hope to be able to gather enough of TSPO from humans to take this research to the next level with increased funding.

“When we compared the two forms of TSPO, normal and mutated, we were able to see substantial differences in structure,” Shelagh Ferguson-Miller, University Distinguished Professor of biochemistry and molecular biology, said. “This could be a clue as to why the human mutant form has an association with anxiety disorders.”

This is a noteworthy occurrence in the world of physiology and neurobiology because of the many implications. For instance: one of the protein samples identified contained a mutant TSPO formation, important because bipolar disease is often associated with a higher probability this particular mutation. The mutant structure is too ridged to bind as successfully with cholesterol, leading to statistically poor cholesterol functionality.

Cholesterol problems of this nature can lead to a problem with steroid hormones. Without a regulated amount of cholesterol, steroids hormones in turn aren’t created as reliably. TSPO plays a part in delivering cholesterol into it’s appropriate place in the mitochondria where it would normally be broken down and reassembled into hormones that deeply affect regular body function.

Ferguson-Miller and her team were able gain a closer look at the crystal structure of the protein by creating an x-ray image of TSPO able to zoom in to the molecular level. This new microscopic imaging technology gave the researchers an far superior understanding of the role TSPO plays in the creation of steroid hormones.

TSPO is also found in higher concentrations near regions of the body that have sustained heavy tissue damage. So, you may have seen some science headlines about a big breakthrough in treating anxiety and depression which could lead to treatments which treat the root cause, inflammation of key areas in the brain. Doctors without access to this equipment can still use the findings to better identify damaged areas of the brain now because they can look for TSPO concentrations in a lower resolution(and lower cost~!) image, like a PET scan.

These next-generation treatments could be years away, she added. This is partly due to TSPO was actually discovered in 1977 when scientists were studying the anxiety-controlling quality of Valium. The TSPO protein was deemed “a peripheral binding site” by most studies and never pursued by big pharmaceutical companies as an economically viable way to sell new medications.

“Many other scientists have studied this protein, but what exactly it is doing has been very difficult to determine,” said Ferguson-Miller. “Drugs and other compounds bind to TSPO, but without knowing the structure, their effects are hard to interpret. Now that we’ve obtained the structure, it could provide important clues regarding anxiety disorders and the basis for a new generation of anti-anxiety drugs.”

So, Michigan State University published a great study about the crystal structure of, TSPO, a protein long associated with several kinds of anxiety problems without ever having been fully understood before now. It will be vastly less difficult to design drugs that bind to the protein in various ways now that we can see close enough to identify the shape of the complicated molecule.

Currently popular anti-anxiety, or anti-depressant drugs are taken by one in ten Americans and often have dangerous side-effects including, suicide, addiction and overdose.

Jonathan Howard
Jonathan is a freelance writer living in Brooklyn, NY

Can Information be Weaponized? Memetic Warfare and the Sixth Domain: Part Two


What role would optical illusions, graffiti and QR code technology play in weaponizing an image, sound, video or string of words to influence or control the human mind? Jonathan Howard takes a look at technology and the theoretical future of psychological warfare with the second part of an ongoing series. This installment of Can Information be Weaponized? is Memetic Warfare and the Sixth Domain: Part Two in which Jonathan Howard continues the train of thought about a possible delivery system for  harmful memes by exploiting common mental weaknesses, including optical illusions, graffiti, and QR Code Technology. If you haven’t read it yet, you should start with Can Information be Weaponized? is Memetic Warfare and the Sixth Domain: Part One.

It’s an aspect of human psychology most readers will already be aware of: optical illusions. As Neil DeGrasse Tyson once pointed out, “an optical illusion is just brain failure”.

People like to trust their perception of what is happening in the world around them but there are circumstances where our perception of an image or set of images can’t be relied on as accurate. An illusion doesn’t have to be optical; we’ve all experienced an earworm, a piece of music, a movie quote or other form of recorded audio, which, once heard, seems to play with vivid realism. An earworm can make a sound seem to play on infinite repeat, often leaving the victim feel plagued by a sound that is not truly there.

Being fooled is a novelty and it can be fun but the video clip below demonstrates how illusions don’t just mess with your eyes(or ears). In certain, often common, circumstances illusory effects can actually modify the way your brain works. In January, 2014, vlogger Tom Scott created a recent video to explain the nature of the McCullough Effect, an optical illusion that can change the way your brain interprets colors in relation to striped patterns.

The video mentions the McCullough Effect can have lasting effects – potentially 3 months. In the interest of remaining unbiased I have not yet experimented but some Reddit users went ahead and tried it with believable results. Try it at your own risk~!

“You couldn’t rub out even half the ‘Fuck You’ signs in the world” ~ Holden Caulfield in J.D. Salinger’s A Catcher in the Rye

It would be difficult to weaponize the principle behind The McCullough Effect because the worm takes several minutes of intentional concentration to take effect. It’s a far cry from Medusa’s statue-creating gaze. Aspects of media can work much faster though. An offensive or upsetting image encountered via social media is often dubbed “cannot be unseen”.  In J.D. Salinger’s A Catcher in the Rye, main character Holden Caulfield laments the human tendency to exploit written language with malice whenever he sees school kids exposed to vulgarity whenever a, “fuck you”, scrawled on a public wall. The illustration below illustrates this point by putting a gratuitous swearword in your head but has another possible harmful-meme delivery system: QR Code

Much in the way you can't unsee a curse word written in a public space, a day may come when a more complicated curse-like state might be induced via QR code.

Much in the way you can’t unsee a curse word written in a public space, a day may come when a more complicated curse-like state might be induced via QR code.

In February, 2014, Dr. Nik Thompson of Murdoch University pointed out QR codes can easily be exploited by cybercriminals because they can’t readily be interpreted by humans without the aid of a machine adding, “There have already been cases of QR codes used maliciously to install malware on devices, or direct them to questionable websites.”

Technically, by exploring the idea of exploited QR code, I’m making the same mistake as Diggins and Arizmendi, regarding compromised computer-assisted operating systems as a form of sixth domain warfare, when that would actually count as the fifth domain, cyber warfare. A compromised operating system on a phone or other smart device might seem like your brain is being attacked but the device is the only thing you’d be losing control of.

A truly weaponized piece of media might combine various elements of what I’ve described.  Weaponized information would have to be:

  • immediately absorbed like graffiti
  • difficult or impossible to unsee like an offensive or disgusting image on the web
  • able to induce or catalyze lasting changes in the mind like the McCullough Effect
  • able to exploit the theoretical, bicameral firmware of the human mind as described in The Origin of Consciousness in the Breakdown of the Bicameral Mind(nonfiction) possibly in the manner of Snow Crash(fiction)
  •  possibly able to exploit the Fifth Domain of Warfare(Cyberspace) to reach the Sixth(The Mind) examples include human reliance on Brain-Computer Interface(BCI) is a major weakness in the modern human psyche, as described by Chloe Diggins and Clint Arizmendi or QR code Malware.

Thanks for reading Can Information be Weaponized? Memetic Warfare and the Sixth Domain: Part Two~! You can go back and read Part One here. Any suggestions, contradictions, likes, shares or comments are welcome.

Jonathan Howard posted this on Monday, February 9th, 2015

[email protected]

 

Jonathan Howard
Jonathan is a freelance writer living in Brooklyn, NY

Can Information be Weaponized? Memetic Warfare and the Sixth Domain: Part One


Can an image, sound, video or string of words influence the human mind so strongly the mind is actually harmed or controlled? Cosmoso takes a look at technology and the theoretical future of psychological warfare with Part One of an ongoing series. This installment of Can Information be Weaponized? Memetic Warfare and the Sixth Domain: Part One is about a possible delivery system for harmful memes. You can click here to jump to Part Two.

Chloe Diggins and Clint Arizmendi wrote an article for Wired Magazine back in Dec., 2012 entitled, Hacking the Human Brain: The Next Domain of Warfare. The piece began:

It’s been fashionable in military circles to talk about cyberspace as a “fifth domain” for warfare, along with land, space, air and sea. But there’s a sixth and arguably more important warfighting domain emerging: the human brain. ~Hacking the Human Brain by Chloe Diggins and Clint Arizmendi, 2012, Wired Magazine

Hacking the Human Brain  concentrated on the vulnerabilities of Brain-Computer Interface or BCI, giving some examples about how ever-increasing human reliance of computer-aided decision making in modern warfare opens users to security risks from weaponized hacking attempts. It’s a great article but the article is not actually discussing that sixth domain it claimed to in that opening paragraph I quoted above.  The attacks described by Diggins and Arizmendi are in the nature of exosuits and mind-controlled drones being overridden by hackers, exhibiting the fifth domain of warfare of the given paradigm. What kind of attack would truly compromise, subjugate the sixth domain, the domain of the mind?

“Wait a minute, Juanita. Make up your mind. This Snow Crash thing—is it a virus, a drug, or a religion?”
Juanita shrugs. “What’s the difference?” ~ From Neil Stephenson’s Snow Crash, 1992

In Neil Stephenson‘s 1992 novel, Snow Crash, the hero unravels a complicated conspiracy to control minds using a complicated image file which taps into the innate, hardwired firmware language the human brain uses as an operating system. By simply viewing an image, any human could be susceptible to a contagious, self-replicating idea. The novel was ahead of its time in describing the power of media and the potential dangers posed by creating immersive, interactive virtual worlds and memes with harmful messages or ideas that can spread virally via social media. In the world of Snow Crash, a simple 2d image was the only technology needed to infect the human mind, forcing the victim to comply. The word and much of the concept of a meme had yet to be developed in 1992 but as the above quote points out, there are several, well tested mind control systems in existence already, including viruses, drugs and religions(Check out Snow Crash by Neil Stephenson at Amazon.com).

Stephenson waxed academic about language, history and the idea that ancient Sumerians had already uncovered this ability to hack the human mind. He later credited a 1976 book by Julian Jaynes, The Origin of Consciousness in the Breakdown of the Bicameral Mind as an influence and inspiration for Snow Crash. In Origin of Consciousness, Jaynes coined the term bicameralism,  hypothetical psychological supposition that the human mind used to be divided into 2 main language functions. One part of the human mind was for speaking and the other was for listening, aka bicameralism. Jaynes claimed this state was normal in primates until a relatively recent change in language and cognition happened to humanity, supposedly about 3000 years ago. Stephenson’s fictional technology attacks modern man’s anthropologically latent compulsion to automatically accept orders when the orders are presented in the correct language.

snow crash

Is a mind-control meme only the stuff of science fiction? In real life, how susceptible are humans to this kind of attack? Check out Can Information be Weaponized? Memetic Warfare and the Sixth Domain Part Two.

Thanks for reading Can Information be Weaponized? Memetic Warfare and the Sixth Domain: Part One~! Any suggestions, contradictions, likes, shares or comments are welcome.

Jonathan Howard posted this on Monday, February 9th, 2015

[email protected]

 

Jonathan Howard
Jonathan is a freelance writer living in Brooklyn, NY

Vaccines and the Psychology of the Anti-Science Movement


One of the things I love about science is the vocabulary that it allows people to use. The whole point of any science is to understand and adapt to the environments we find ourselves in. People who are particularly good at explaining this vocabulary make good or even great scientists but the ideas scientists explain are not dependent on any one human.

Sometimes the truth is harsh. Science sometimes allows us to see a harsh aspect of reality and rather than accept that harsh reality, some people search for a second opinion, in hopes that bad news is not true. This emotional state makes people vulnerable to misinformation, to anyone who might want to exploit that vulnerability. To me, science offers a way to look at those harsh realities for what they are without emotions clouding the ability to understand. The scientific method isn’t just a good way to examine reality, it’s the only way that guarantees the available truth can be understood.

I’m gonna use vaccination as an example of a harsh reality that people don’t always readily accept. I’ve had to go through the debate with various friends and family for years. The vaccination debate has half a dozen easily debunked, unreasonable reasons for not vaccinating humans against diseases. When I point out the science behind my arguments for vaccination they are met with a bizarre suspicion. Without going too much into the ridiculous anti vaccine argument, the anti-science part of it goes something like this:

The source of this scientific claim is suspect so the science itself is suspect. You may have found an article or study that proves my anti vaccination argument wrong but you have to consider the source. Some people write these studies or orchestrate them to show results that are not necessarily accurate.

Why it’s wrong:

You can use the scientific method to reevaluate any study. Science is like math. People can do math incorrectly and get a wrong answer but that doesn’t make math itself wrong. Badly done science doesn’t mean that the scientific method is bad. That’s what I mean when I say the scientific method is the only way. It’s the only logical way to understand literally anything. Saying you don’t trust it is like saying you don’t trust arithmetic.

So, the antivaccination argument that you can’t trust a study is beside the point.  I agree that no one should blindly trust any scientific claim. Not being able to readily rust information is a problem but the solution to the problem is to use the scientific method to weed out bad science. A study can be funded and published by a biased source and still be good science. By using the scientific method you can tell the difference between good and bad information.

We live in a time where we are assaulted by information. The antivaccination movement is a great example of how compelling bad science can become when the audience isn’t using the scientific method to parse the information they are reading. The antivaxxers are wrong but the misinformation has a chance to take root in the collective psyche of modern man because of how available information itself is. People without a solid understanding of the scientific method can’t follow the actual debate and must resort to whichever side wrote the most emotionally compelling argument. Not being able to tell what is true or untrue makes people suspicious and even paranoid. Learning and using the scientific method is crucial to the modern internet experience. It’s the only way to see what’s really happening.

 

Jonathan Howard
Jonathan is a freelance writer living in Brooklyn, NY